Clinical labs performing next-generation sequencing (NGS) demand more from a Laboratory Information Management System (LIMS) than either non-clinical NGS labs or clinical labs delivering non-NGS tests. That’s because NGS puts unique challenges on the infrastructure required to deliver reliable, high-quality results in a cost-effective, timely, and regulatory-compliant manner. We’ve had a lot of conversations with our NGS…

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This is part three of our series on life in a CLIA lab. The previous two blogs in this series explored the transition from working in a research-based facility to moving to a CLIA lab and bringing NGS into a Sanger Lab.  In a Bringing Next-Generation Sequencing into a Sanger Lab, I discussed implementing NGS workflows in a Sanger sequencing…

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This is part two of our series on life in a CLIA lab. The first blog in this series explored the transition from working in a research-based facility to moving to a CLIA lab.  For the last two decades, Sanger sequencing was the gold standard in the clinical lab. It was perfect for the era when most genetic tests…

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In a recent blog, Informatics Challenges in Pharma and Biopharma R&D, we identified five major challenges facing R&D and IT managers in pharma and biopharma companies as they strive to equip their researchers with modern, flexible and responsive informatics tools: Managing New Science Dealing with Change Integrating Old and New Systems Collaboration and Externalization Harmonization and Simplification…

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Operationalizing processes is a critical first step for labs running next-generation sequencing (NGS). By defining specific, routine lab workflows and operations, labs can keep scientists and technicians on task while supporting them in delivering quality results efficiently. In addition, setting defined tasks to undertake and complete enables labs to more easily set metrics tied to specific…

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Labs seeking to adopt next-generation sequencing (NGS) learn quickly that the technology requires them to think differently about how to conduct lab work and organize themselves for success. That’s because NGS processes are not just complex, but constantly evolving with the introduction of new instrumentation and sequencing methodologies. Add to that the data management challenge…

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Preconfigured workflows for a variety of instrumentation and kits help a diverse set of organizations and labs capitalize on genomics data Branford, CT – September 29, 2015 – Core Informatics, a developer of data management software used to accelerate scientific innovation, today announced new successful production deployments of their preconfigured workflow applications for next-generation sequencing (NGS)…

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Powering Next-Generation Sequencing – Apps for NGS LIMS No two labs are the same. In the Next Generation Sequencing (NGS) field we believe that to be especially true, but it is one thing to have a belief or a hypothesis, and another to validate it. To test our hypothesis we decided to run a simple…

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The Enterprise Group faced several projects which would use Next Generation Sequencing for population scale projects in numbers suitable for high throughput sequencing.   As a result, Life Technologies turned to a partner who could help build an informatics system to manage workflows and data.  That partner is Core Informatics. The group worked closely with Core…

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“There is great teamwork with Core on these projects.” Devin Dressman is the Associate Director of the Enterprise Genomics Solutions for Thermo Fisher Scientific. Dressman is the head Lab Architect for the Enterprise group — a person who can envision a plan to make a lab work. And this Lab Architect, when faced with several…

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