Posts Tagged ‘NGS LIMS’

Using Core LIMS to Support Clinical & Research Genomics Workflows

Research Genomics Workflows Core Informatics and Mount Sinai Webinar We hope you were able to join us on April 21st for our webinar on How Mount Sinai Uses LIMS to Support Clinical & Research Genomics Workflows delivered by Todd E. Arnold, PhD., Managing Director, Mount Sinai Genetic Testing Laboratory and joined by Dan Huston, Applications Manager, Genomics, Core…

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Five LIMS Software Capabilities Clinical NGS Labs Need

Clinical labs performing next-generation sequencing (NGS) demand more from a Laboratory Information Management System (LIMS) than either non-clinical NGS labs or clinical labs delivering non-NGS tests. That’s because NGS puts unique challenges on the infrastructure required to deliver reliable, high-quality results in a cost-effective, timely, and regulatory-compliant manner. We’ve had a lot of conversations with our NGS lab…

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Implementing a New NGS System in a Clinical Lab

This is part three of our series on life in a CLIA lab. The previous two blogs in this series explored the transition from working in a research-based facility to moving to a CLIA lab and bringing NGS into a Sanger Lab.  In a Bringing Next-Generation Sequencing into a Sanger Lab, I discussed implementing NGS workflows in a Sanger sequencing…

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Working in a CLIA Lab

Moving from Research to Working with CLIA Lab Regulations Moving to a CLIA lab after working in a research-based facility involved a steep learning curve. My attention was split between sequencing and learning CLIA and HIPAA rules and regulations, learning how to validate tests, software, and instruments, as well as learning the ropes of new documentation.  Needless to say,…

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Implementing NGS, Industry Tip #1: Operationalize Processes

Labs seeking to adopt next-generation sequencing (NGS) learn quickly that the technology requires them to think differently about how to conduct lab work and organize themselves for success. That’s because NGS processes are not just complex, but constantly evolving with the introduction of new instrumentation and sequencing methodologies. Add to that the data management challenge…

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Launch14 Review – Life Technologies – Thermo Fisher Scientific

The Enterprise Group faced several projects which would use Next Generation Sequencing for population scale projects in numbers suitable for high throughput sequencing.   As a result, Life Technologies turned to a partner who could help build an informatics system to manage workflows and data.  That partner is Core Informatics. The group worked closely with Core…

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Legal Obligations Surrounding NGS Data in the Cloud

Facilitating Compliance with Federal Regulations in the World of Cloud Computing The privacy of the patient is always a top priority for scientists and is especially important in the case of genome and exome sequencing. NGS labs are covered entities, meaning they create, maintain, transfer, use, and disclose personal health information (PHI). Therefore, they are…

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The Optimal Design for a NGS LIMS

As the cost of sequencing the human genome continues to drop, the field of Next Generation Sequencing is experiencing dramatic growth. Some estimates put the market at 2.7 billion by 2017. With the decrease in cost, the industry is seeing an increase in use by doctors and researchers. Core Informatics has created a Next-Generation Sequencing…

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